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About TCEQ Development Support Documents (DSDs) for Effects Screening Levels (ESLs) and Air Monitoring Comparison Values (AMCVs)

A Development Support Document summarizes how chemical-specific toxicity values were derived based on published guidelines (RG-442).

Files linked from this page are in Portable Document Format (PDF) Adobe Acrobat PDF Document. (Help with PDF.)

What is a Development Support Document?

A Development Support Document (DSD) summarizes how chemical-specific toxicity values were derived based on RG-442, Guidelines to Develop Effects Screening Levels, Reference Values, and Unit Risk Factors.

When are Proposed and Final DSDs Published?

A proposed DSD is published at the TCEQ web site for a 60-day public review and comment period. After public comments are received, the TS will address and resolve all relevant issues and make scientifically defensible changes to the DSD and toxicity values, if needed.

The final DSDs with a Response to Comments, if applicable, are then published on the TCEQ website. Registrants on the Toxicology Announcement List will be notified by e-mail when proposed or final DSDs are posted.

Procedure to Submit Comments

The TD is not currently accepting public comments. Sign up to receive ESL List, AMCV List, and other related toxicology announcements by joining the Toxicology Announcement List.

Contact the TCEQ About DSDs and Fact Sheets

877-992-8370 (toll free) or 512-239-3900


Write: Texas Commission on Environmental Quality

Toxicology Division, MC 168

P.O. Box 13087

Austin, TX 78711-3087

POSITION PAPER – Systematic Review and Evidence Integration

WHITE PAPER – TCEQ Guidelines to Develop 24-Hour Inhalation Reference Values

WHITE PAPER – Updated Recommendations for Animal-To Human Inhalation Dosimetry

The Toxicology Division (TD) of the Texas Commission on Environmental Quality (TCEQ) amended Section 3.9.1, Default Dosimetry Adjustments for Gases in the October 2012 regulatory guidance document, TCEQ Guidelines to Develop Toxicity Factors (RG-442). This section was updated to include information on animal-to-human inhalation gas dosimetric adjustments based on recommendations in Advances in Inhalation Gas Dosimetry for Derivation of a Reference Concentration (RfC) and Use in Risk Assessment (USEPA 2012, EPA/600/R-12/044). Please refer to the White PaperAdobe Acrobat PDF Document for a discussion of the changes.

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For instructions on how to join the Toxicology Announcement List, click here.