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About TCEQ Development Support Documents (DSDs) for Effects Screening Levels (ESLs) and Air Monitoring Comparison Values (AMCVs)

A Development Support Document summarizes how chemical-specific toxicity values were derived based on published guidelines (RG-442).
What is a Development Support Document?

A Development Support Document (DSD) summarizes how chemical-specific toxicity values were derived based on RG-442, Guidelines to Develop Effects Screening Levels, Reference Values, and Unit Risk Factors.

When are Proposed and Final DSDs Published?

A proposed DSD is published at the TCEQ web site for a 90-day public review and comment period. After public comments are received, the TD will address and resolve all relevant issues and make scientifically defensible changes to the DSD and toxicity values, if needed.

The final DSDs with a Response to Comments, if applicable, are then published on the TCEQ website. Registrants on the Toxicology Announcement List will be notified by e-mail when proposed or final DSDs are posted.

Current Public Comment Period

The Toxicology Division is accepting public comments on the Systematic Review and Evidence Integration for 16 PFAS and the Draft Development Support Document for Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonic Acid (PFOS) and Salts through January 30, 2026.

Systematic Review and Evidence Integration for 16 Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS)

Draft Development Support Document: Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonic Acid (PFOS) and Salts

Associated excel files:

Systematic Review for 16 PFAS

Systematic Evidence Map for 16 PFAS 

How To Submit Comments

Please submit comments no later than 5 pm on January 30, 2026 to one of the options listed:

e-mail: tox@tceq.texas.gov

Regular mail:

Toxicology, Risk Assessment, and Research Division, MC 168

Texas Commission on Environmental Quality

P.O. Box 13087 Austin, TX 78711-3087

Mail delivery services:

Toxicology, Risk Assessment, and Research Division, MC 168

Texas Commission on Environmental Quality

12100 Park 35 Circle, Bldg. F

Austin, TX 78753

Sign Up to Receive ESL List, AMCV List, and Other Related Toxicology Announcements

For instructions on how to join the Toxicology Announcement List, click here.