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Final Development Support Documents (DSDs)

DSDs detail how Effects Screening Levels (ESLs), inhalation Reference Values (ReVs), and inhalation Unit Risk Factors (URFs) were derived for specific chemicals. This page also links to Fact Sheets which summarize information used by the TCEQ Toxicology Division to develop those values.

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Click on the substance name to view its DSD. Click on “Fact Sheet” to view summary information about the substance.

magnifying glass Definitions of ESLs, REVs & AMCVs

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A B C D E F G H I J K L M N O P R S T U V W X Y Z

A

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Acetone
 67-64-1 Yes December 18, 2013
Revised Odor:
September 1, 2015
Acrolein
107-02-8 Yes November 19, 2010
Chronic ReV:
March 14, 2014
24 hr and Odor:
September 14, 2015
Short-term ESL:
February 4, 2016
Acrylonitrile
 107-13-1 Yes December 18, 2013
Revised Odor: September 14, 2015
Ammonia
7664-41-7 No June 16, 2014
Revised Odor: September 14, 2015
Arsenic and Inorganic Arsenic Compounds
 7440-38-2
(Arsenic)		 Yes July 31, 2012

B

Substance Name Chemical Abstract Service Registry Number
(CASRN)		 Public Comments Date Finalized
Revision Date(s) if applicable
Benzene
71-43-2 Yes October 15, 2007
Revised: September 14, 2015
Butadiene, 1,3-
106-99-0 Yes August 7, 2008
24-Hour: September 14, 2015
Butane, All Isomers

n-Butane
Isobutane


106-97-8
75-28-5

 Yes July 31, 2012
Revised: September 14, 2015
Butene, 1-
106-98-9 Yes April 15, 2008
Revised: March 14, 2014
Revised Odor:
September 14, 2015
Butene, 2-

cis and trans
cis-butene, -2
trans-butene, -2


107-01-7
590-18-1
624-64-6

 Yes April 15, 2008
Revised: March 14, 2014
Revised Odor:
September 14, 2015
Butoxyethanol
111-76-2 Yes October 15, 2007
Revised Odor:
September 14, 2015
Butyl acetate, n 123-86-4 Yes December 29, 2010
Revised: March 14, 2014
Revised Odor:
September 14, 2015
Butyraldehyde
 123-72-8 Yes March 14, 2014
Revised Odor:
September 14, 2015

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C

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Cadmium and Cadmium Compounds

Cadmium
Cadmium Carbonate
Cadmium Chloride
Cadmium Oxide
Cadmium Sulfate
Cadmium Sulfide


7440-43-9
513-78-0
10108-64-2
1306-19-0
10124-36-4
1306-23-6

 No September 2, 2016
Carbon Disulfide
 75-15-0 No September 4, 2015 Revised March 7, 2017
NEW Carbon Tetrachloride
 56-23-5 NEW Yes April 5, 2024
Chlorine
 7782-50-5 Yes November 29, 2017
Chromic Acid Mist
 7738-94-5 No October 27, 2014
Chromium

(All Compounds Except Hexavalent Chromium)
Elemental Chromium
Trivalent Chromium


7440-47-3
16065-83-1

 No October 8, 2009 Accessible 2013
Chromium (Hexavalent)

Ammonium dichromate
Calcium chromate
Sodium chromate
Chromium trioxide
Sodium dichromate
Sodium dichromate, dihydrate
Lead chromate
Potassium chromate
Potassium dichromate
Strontium chromate
Zinc chromate

18540-29-9
7789-09-5
13765-19-0
7775-11-3
1333-82-0
10588-01-9
7789-12-0
7758-97-6
7789-00-6
7778-50-9
7789-06-2
13530-65-9

 Yes August 4, 2014
Chromium (Hexavalent) Oral Reference Dose
18540-29-9 Yes September 23, 2016
Cobalt and Cobalt Compounds
 7440-48-4
(Cobalt)		 No August 16, 2017
Crotonaldehyde

trans-crotonaldehyde
cis-crotonaldehyde

4170-30-3
123-73-9
15798-64-8

 No August 4, 2014 Revised September 4, 2015 Revised August 23, 2016

D

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments   Date Finalized Revision Date(s) if applicable
Decane, All Isomers

n-Decane

Other 74 Isomers
124-18-5		 No   August 16, 2017
Dibutylamine
 111-92-2 No   July 8, 2016
Dichlorobenzene, 1,4-
106-46-7 No  

February 13, 2009
Revised: March 14, 2014
Revised Odor:
September 14, 2015
Dichloroethylene, 1,1-
75-35-4 No   October 15, 2007
Accessible 2013
Diethanolamine and Triethanolamine

Diethanolamine
Triethanolamine
111-42-2
102-71-6		 No   June 28, 2018
Diethylamine
109-89-7 No   December 4, 2015
Diisopropylamine
 108-18-9 No   July 8, 2016

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E

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Ethylbenzene
 100-41-4 No Final, November 19, 2010 Accessible 2013 Revised Odor Value, September 14, 2015
Ethylene
 74-85-1 Yes Final, April 15, 2008 Accessible 2013 Revised Odor Value, September 14, 2015
Ethylene Dibromide
 106-93-4 No November 29, 2017
Ethylene Dichloride
 107-06-2 Yes March 23, 2016
Ethylene Glycol
 107-21-1 Yes February 2016
Ethylene Oxide

75-21-8 Yes May 15, 2020

F

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Formaldehyde
50-00-0 Yes

Yes (24-hour)

August 7, 2008; Accessible 2013 24-Hour Reference Value: September 14, 2015

H

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Heptane, All Isomers

n-heptane
2,2-dimethylpentane
2,3-dimethylpentane
2,4-dimethylpentane
3,3-dimethylpentane
2-methylhexane
3-methylhexane
3-ethylpentane
2,2,3-trimethylbutane


142-82-5
590-35-2
565-59-3
108-08-7
562-49-2
591-76-4
589-34-4
617-78-7
464-06-2

 No September 30, 2016
Hexamethylenediamine
 124-09-4 No Final May 18, 2015 Revised Odor Value, September 14, 2015
Hexane, All Isomers

n-Hexane
Other 4 Isomers
110-54-3		 No August 16, 2017
Hydrogen Chloride
 7647-01-0 Yes October 8, 2009 Revised: March 14, 2014
Hydrogen Fluoride and Other Soluble Inorganic Fluorides
 7664-39-3 Yes October 8, 2009 Accessible 2013 Revised Odor Value: September 14, 2015

I

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Isobutene
 115-11-7 Yes April 15, 2008 Revised: March 14, 2014 Revised Odor Value, September 14, 2015
Isoprene

 78-79-5 No March 8, 2018

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M

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Manganese and Inorganic Manganese Compounds
 7439-96-5 Yes November 29, 2017
Methacrolein
 78-85-3 No October 8, 2009 Revised: March 14, 2014
Methanol
 67-56-1 Yes March 14, 2014 Revised Odor Value: September 14, 2015
Methoxysilanes (Tri- and Tetra-)

Trimethoxysilane
Methyltrimethoxysilane
Vinyltrimethoxysilane
3-Chloropropyltrimethoxysilane
Tetramethoxysilane


2487-90-3
1185-55-3
2768-02-7
2530-87-2
681-84-5

 Yes January 15, 2016
Methyl Amyl Ketone
 110-43-0 No October 15, 2007 Accessible 2013 Revised Odor Value, September 14, 2015
Methyl Ethyl Ketone
 78-93-3 No November 19, 2010 Accessible 2013 Revised Odor Value, September 14, 2015
Methylene Chloride
 75-09-2 No June 1, 2011 Accessible 2013
Methylene Diphenyl Diisocyanate and Hexamethylene Diisocyanate

4,4-Methylene Diphenyl Diisocyanate (MDI), All Isomers
1,6-Hexamethylene Diisocyanate (HDI), All Isomers

101-68-8
822-06-0		 Yes December 9, 2019
Monoethanolamine
 141-43-5 No September 4, 2015

N

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Nickel and Inorganic Nickel Compounds

Nickel
Nickel Sulfate
Nickel Subsulfide
Nickel Oxide
Nickel Chloride


7440-02-0
7786-81-4
12035-72-2
1313-99-1
7718-54-9

 Yes June 1, 2011 Accessible, 2013 Revised, July 26, 2017
Nonane, All Isomers

n-Nonane Other 34 Isomers

111-84-2		 No September 30, 2016

O

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Octane, All Isomers

Octane
2,2,4-Trimethylpentane (Isooctane)
Other 16 Isomers

111-65-9
540-84-1		 No September 30, 2016

P

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Pentane, All Isomers

n-Pentane
Isopentane
Neopentane


109-66-0
78-78-4
463-82-1

 Yes July 29, 2011 Accessible 2013 Revised Odor Value: September 14, 2015
Pentene, All Isomers

1-pentene
c-2-pentene
t-2-pentene


109-67-1
627-20-3
646-04-8

 No October 15, 2007 Revised August 4, 2014 Revised September 14, 2015
Phenol
 108-95-2 No August 4, 2014 Revised Odor Value, September 14, 2015
Propionaldehyde
 123-38-6 Yes September 14, 2015

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S

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Silica, Amorphous and Other Non-Crystalline Forms

fused precipitated silica and silica gel
pyrogenic colloidal silica
silica fume
synthetic amorphous silica
uncalcined diatomaceous earth

60676-86-0

112926-00-8
112945-52-5
69012-64-2
7631-86-9
61790-53-2

 Yes July 29, 2011 Accessible 2013

Silica, Crystalline Forms

Silica, Crystalline Forms (24-hour)

cristobalite
quartz
tridymite
tripoli
14464-46-1
14808-60-7
15468-32-3
1317-95-9

Yes

Yes (24-hour)

 October 8, 2009 Accessible 2013
December 11, 2020
Styrene
 100-42-5 Yes August 7, 2008 Accessible 2013

T

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Tert-Butyl Alcohol
 75-65-0 Yes March 15, 2023
Tetrachloroethylene(PCE)
 127-18-4 Yes April 15, 2008 Accessible 2013 Revised Odor Value: September 14, 2015
Texanol
 25265-77-4 Yes April 15, 2008 Accessible 2013 Revised Odor Value, September 14, 2015
Toluene
 108-88-3 Yes April 15, 2008 Revised Odor ESL: March 21, 2014 Revised Odor ESL: September 14, 2015
Trichloroethane, 1,1,1-
 71-55-6 No June 1, 2011 Accessible 2013 Revised Odor Value, September 14, 2015
Trimethylbenzenes (TMB)

1,2,3-TMB
1,2,4-TMB
1,3,5-TMB
Mixed Isomers


526-73-6
95-63-6
108-67-8
25551-13-7

 No September 4, 2015

V

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Vinyl Acetate
 108-05-4 Yes September 4, 2015
Vinyl Chloride
 75-01-4 No February 13, 2009 Accessible 2013
Vinylcyclohexene, 4-
 100-40-3 Yes July 29, 2011 Accessible 2013 Revised Odor Value, September 14, 2015

X

Substance Name Chemical Abstract Service Registry Number (CASRN) Public Comments Date Finalized Revision Date(s) if applicable
Xylenes Mixture
 1330-20-7
108-38-3
95-47-6
106-42-3		 Yes February 13, 2009 Revised Odor: March 21, 2014 Revised Odor: September 14, 2015

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